Please use this identifier to cite or link to this item: https://csirspace.foodresearchgh.site/handle/123456789/1615
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dc.contributor.authorOtunola, G.-
dc.contributor.authorTalabi, O.-
dc.contributor.authorOduro-Yeboah, C.-
dc.contributor.authorNyarko, J.-
dc.contributor.authorOjo, O.-
dc.contributor.authorAfolayan-
dc.date.accessioned2025-03-17T11:44:01Z-
dc.date.available2025-03-17T11:44:01Z-
dc.date.issued2023-
dc.identifier.urihttps://csirspace.foodresearchgh.site/handle/123456789/1615-
dc.descriptionResearch Articleen
dc.description.abstractThe therapeutic benefits of fermented foods in the treatment and prevention of Type 2 diabetes mellitus have been reported. Aim: Inhibitory effect of fermented rice beverages on α-amylase, αglucosidase and pancreatic lipase was evaluated. Method: Two fermented rice beverages-fermented rice alone (FKR) and fermented rice plus roasted peanuts (FKRG) were produced using spontaneous fermentation. Capacity of the beverages to inhibit alpha-glucosidase, alpha-amylase and pancreatic lipase in vitro was evaluated and compared with standards (positive controls). Results: FKR exerted inhibition of α-glucosidase between 9.23-21.11% and FKRG 1.11-17.36% at the various concentrations respectively, with both samples showing the most significant inhibition (about 20%) at 125 μg/mL. FKRG exhibited greater alpha-amylase inhibition activity than FKR, but for both samples, the most significant (P < 0.05) inhibition occurred at 500 μg/mL. With pancreatic lipase, no significant inhibition was observed for both FKR and FKRG at the tested concentrations compared to Orlistat used as control; however, at 31.25 μg /mL FKRG showed an inhibitory effect of approximately 15%, which was not evident at higher concentrations. Conclusion: Low to moderate inhibition of α-amylase, α-glucosidase and pancreatic lipase by both FKR and FKRG, showed that the fermented rice beverages have potential to modulate hyperglycemia in type 2 diabetes in vitro. This is an indication that fermented rice beverage could prevent postprandial hyperglycemia in vivo.en
dc.language.isoenen
dc.subjectfermented beveragesen
dc.subjecttype 2 diabetesen
dc.subjectpostprandial hyperglycemiaen
dc.subjectcarbohydrate metabolizing enzymesen
dc.titleFermented rice beverages modulate key enzymes related to type 2 diabetes in vitroen
dc.typeArticleen
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